Central administration of palmitoylethanolamide lowers hyperalgesia in mice by way of inhibition of NF‐κB nuclear signalling in dorsal root ganglia. Eur J PharmacolThe exogenous administration of PEA might in such conditions provide to replenish amounts of endogenous PEA, restoring its protective, anti-inflammatory and analgesic results. Interes
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Clinicaltrials.gov was looked for registered research protocols. The key terms “palmitoylethanolamide” and “agony” resulted in 13 entries, of which three were being done. None of them fulfilled our eligibility criteria.The exogenous administration of PEA may well in this sort of instances provide to replenish amounts of endogenous PEA, rest